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Standard and intermediate risk acute lymphoblastic leukemia in Poland: A report of the Polish Children's Leukemia/Lymphoma Study Group |
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| Authors: | URSZULA RADWANSKA DANUTA MICHALEWSKA PAWEL KOLECKI JERZY ARMATA WALENTYNA BALWIERZ JANINA BOGUSLAWSKA-JAWORSKA ALICJA CHYBICKA ROMANA CYKLIS JERZY KOWALCZYK MARIA OCHOCKA KATARZYNA PAWELEC ROMA ROKICKA-MILEWSKA DANUTA SONTA-JAKIMCZYK GRAZYNA SLADKOWSKA ELZBIETA ZELENAY |
| Abstract: | A total of 527 children with acute lymphoblastic leukaemia (ALL) from the most frequent risk groups: standard risk group (SRG) and intermediate risk group (IRG) were treated between 1987 and 1991 according to an intensified treatment program (based on the BFM protocol) including the use of an intermediate dose of methotrexate in the IRG. A comparison of the treatment results in this group from 513 children treated between 1981 and 1987 indicates that the chance for a 6 year event-free survival has increased to 73% (previously 55%). |
| Keywords: | acute lymphoblastic leukemia chemotherapy childhood intermediate risk standard risk |