壮族2型糖尿病患者高血压的影响因素分析

目的 探讨壮族2型糖尿病(T2DM)患者高血压的影响因素,以期发现高血压危险人群,并采取措施减少心血管疾病的发生.方法 回顾性分析2013年1月—2018年12月在南宁市、崇左市、百色市、河池市、马山县5家壮族人群聚居区医院的壮族T2DM患者相关资料,包括人口学特征、血糖和血脂等生物化学指标及生活方式等情况.采用单因素...

The analysis of influencing factors for hypertension in type 2diabetic patients of Zhuang nationality*

Objective To investigate the risk factors for hypertension in patients of Zhuang nationality withtype 2 diabetes mellitus (T2DM), and therefore to find out the population at risk of hypertension, so as to takepreventive measures to reduce the incidence of cardiovascular diseases. Methods Data on T2DM patients ofZhuang nationality from 5 hospitals in Guangxi from January 2013 to December 2018 were collected and analyzedretrospectively, including demographic characteristics, biochemical indicators such as blood sugar and blood lipids,and lifestyle. Univariate analysis and multiple linear regression analysis were used to explore the risk factors forhypertension in T2DM patients of Zhuang nationality. Results A total of 1 598 T2DM patients of Zhuangnationality were enrolled, and were divided into normal blood pressure group (306 cases), prehypertension group(436 cases), and hypertension group (856 cases). Correlation analysis was performed based on systolic bloodpressure (SBP) and diastolic blood pressure (DBP). The results showed that SBP was positively correlated with age, duration of diabetes mellitus, family history of cardiovascular diseases, body mass index (BMI), glycosylatedhemoglobin (HbAlc), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides (TG), totalcholesterol (TC), and high-sensitivity C-reactive protein (hs-CRP) (P < 0.05), while SBP was negatively correlatedwith smoking, alcohol consumption, physical activity and 2-hour plasma glucose (2hPG) (P < 0.05). Besides, DBPwas positively correlated with age, duration of diabetes mellitus, family history of cardiovascular diseases, BMI,fasting plasma glucose (FPG), HbAlc, HDL, LDL, TG, TC, and hs-CRP (P < 0.05), but was negatively correlatedwith physical activity (P < 0.05). The multiple linear regression analysis showed that age, physical activity, familyhistory of cardiovascular diseases, BMI, HbAlc, HDL, LDL, and hs-CRP were independent risk factors for increasedSBP in T2DM patients of Zhuang nationality (P < 0.05). In addition, age, physical activity, BMI, FPG, HbAlc, HDL,TC, hs-CRP were independent risk factors for increased DBP in T2DM patients of Zhuang nationality (P < 0.05).Conclusions The age, physical activity, family history of cardiovascular diseases, BMI, FPG, HbAlc, HDL, LDL,TC and hs-CRP are the influencing factors for hypertension in T2DM patients of Zhuang nationality.