清胃散联合头孢拉定治疗牙周病患者效果观察及对菌斑指数、牙周袋探针深度、龈沟出血指数的影响

目的  探讨清胃散联合头孢拉定治疗牙周炎患者效果观察及对菌斑指数、牙周袋探针深度、龈沟出血指数的影响。方法  按照随机数字表法将本组纳入的143例患者随机分为观察组（n =51）、对照组A（n =46）和对照组B（n =46）。观察组给予清胃散联合头孢拉定治疗，对照组A单用头孢拉定治疗，对照组B单用清胃散治疗。3组患者治疗疗程均为2周。疗程结束后比较两组菌斑指数、牙周袋探针深度、龈沟出血指数变化、疗效及不良反应发生情况。结果  3组患者菌斑指数、牙周袋探针深度、龈沟出血指数治疗后较治疗前显著降低，差异有统计学意义（P <0.05）；观察组菌斑指数、牙周袋探针深度、龈沟出血指数治疗后显著低于对照组A和对照组B，差异有统计学意义（P <0.05）；对照组A菌斑指数、牙周袋探针深度、龈沟出血指数治疗后显著低于对照组B，差异有统计学意义（P <0.05）；观察组总有效率（96.07%）显著高于对照组A（80.44%）和对照组B（75.22%），差异有统计学意义（P <0.05）；3组患者治疗中均未发生明显不良反应。结论  清胃散联合头孢拉定治疗牙周病患者效果显著，可明显降低患者菌斑指数、牙周袋探针深度、龈沟出血指数，改善临床症状，具有重要研究意义。

Efficacy of Qingwei power combined with Cefradine in treatment of periodontal disease and effect on plague index, periodontal pocket depth of probe and sulcus bleeding index

Objective To investigate the clinical efficacy of Qingwei power combined with Cefradine in the treatment of periodontal disease and effect on the plague index, periodontal pocket depth of probe sulcus bleeding index. Methods A total of 143 cases of patients who were enrolled by random number table were divided into observation group (n = 51), control group A (n = 46) and control group B (n =46). The observation group was treated with Qingwei power combined with Cefradine, the control group A was treated with Cefradine alone, and the control group B was treated with Qingwei power alone; all the three groups received treatment for 2 weeks. After treatment, plague index, periodontal pocket depth of probe, change of sulcus bleeding index, clinical efficacy and occurrence of adversereactions were compared among the three groups. Results In all the three groups, the plague index, the periodontal pocket depth of probe and the sulcus bleeding index after treatment were significantly lower than those before treatment (P < 0.05). After treatment, the plague index, the periodontal pocket depth of probe and the sulcus bleeding index in the observation group were significantly lower than those in the two control groups (P < 0.05); the plague index, the periodontal pocket depth of probe and the sulcus bleeding index in the control group A were significantly lower than those in the control group B (P < 0.05). The total efficiency of the observation group (96.07%) was significantly higher than that in both the control group A (80.44%) and the control group B (75.22%) with statistical difference (P < 0.05), and no adverse reaction was observed in any group. Conclusions The clinical efficacy of Qingwei power combined with Cefradine in the treatment of periodontal disease is significant, and could obviously decrease plague index, periodontal pocket depth of probe and sulcus bleeding index and improve the clinical symptoms, with important research significance.