某市2013～2015年男男性行为人群人类免疫缺陷病毒新发感染研究

目的了解淮安市男男性行为（MSM）人群中人类免疫缺陷病毒（HIV）新发感染情况及其影响因素。方法2013～2015 年通过网络招募MSM，进行问卷调查以及实验室检测；检出的HIV 阳性样本再应用BED HIV IgG 捕获酶免疫法（BED-CEIA）检出其中的新发感染样本，计算新发感染率。以HIV 阴性为对照，采用Logistic 回归分析探讨其影响因素。结果2013～2015 年共招募1 202 名调查对象，新发感染率分别为1.81%、1.89%和3.18%，3年间差异无统计学意义（P >0.05）。多因素分析显示在本地居住时间和梅毒感染是HIV感染的主要危险因素。结论淮安市MSM人群HIV 新发感染率较其他地区低，但仍在不断增长，影响新发感染的主要因素为本地居住时间和梅毒感染，应加强MSM 人群的干预力度，同时开展多种疾病联合监测，遏制疾病扩散。

A survey of HIV incidence among men who had sex with men in Huaian from 2013 to 2015

Objective To investigate the incidence of human immunodeficiency virus (HIV) infection and HIV influencing factors among men who had sex with men (MSM) in Huaian city. Methods MSM were enrolled by network from 2013 to 2015. HIV information was collected by questionnaire, and the samples were taken from MSM and tested to find HIV seropositve samples. Then these samples were tested with BED HIV IgG capture enzyme immunoassay (BED-CEIA) to find newly-infected samples and the annual HIV incidence was calculated. Compared with the HIV negative cases, the influencing factors were explored by logistic regression. Resluts A total of 1,202 MSM were recruited from 2013 to 2015. HIV recent infectious incidences were 1.81% , 1.89% and 3.18% respectively, and there were no significant differences among the three years. Multiple factor analysis showed that short local residence time (less than 2 years) and syphilis infection were the major risk factors for HIV infection. Conclusions HIV recent infectious incidence among MSM in Huaian is still growing, but is lower than that in other regions. The main risk factors are short local residence time (less than 2 years) and syphilis infection. Powerful prevention and control effort must be made in MSM, and joint surveillance of multiple diseases should be implemented to curb the spread of HIV in this population group.