联合微信群的个体化健康教育对2型糖尿病患者认知功能的影响

目的  探讨联合微信群的个体化健康教育对2型糖尿病（T2DM）患者认知功能的影响。方法  53例T2DM患者，男性30例，女性23例，应用重复成套神经心理状态测验（RBANS）量表评价患者认知功能，对患者进行院内宣教、院外随访及电话随访等个体化健康教育，联合微信群进行教育，干预6个月后，观察T2DM患者教育前后空腹血糖、糖化血红蛋白及认知功能的变化，探讨认知增值的相关因素。结果  联合微信群的个体化健康教育后的空腹血糖（FPG）、糖化血红蛋白（HbA1c）值低于教育前（P <0.05）；联合微信群的个体化健康教育后的延迟记忆评分（86.9±13.5 vs 80.4±14.9）高于个体化健康教育前（P <0.05）；经6个月联合微信群的个体化健康教育后，HbA1c下降值与延迟记忆升高值呈正相关（r =0.353，P =0.020），与重复成套神经心理状态测验标准分升高值呈正相关（r =0.327，P =0.045）。线性回归分析后，HbA1c下降值与延迟记忆升高值的相关关系仍存在（P <0.05）。结论  联合微信群的个体化健康教育能明显改善T2DM患者认知功能，尤其在延迟记忆方面。

Influence of using individual health education and WeChat on cognitive performance in patients with type 2 diabetes

Objective To investigate the influence of using individual health education and WeChat on cognitive performance in patients with type 2 diabetes. Methods The demographic and clinical data of 53 type 2 diabetes (T2DM) (male : female = 30 : 23) patients were collected. The repeatable battery for the assessment of neuropsychological status (RBANS) was applied to assess their cognitive function. The patients received individual health education for six months. The fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c) and cognitive performance were measured and compared before and after education, the factors related to the increased value of cognitive performance in T2DM patients were investigated. Results In the T2DM patients, the FPG and HbA1c values after individual and WeChat health education were lower than those before education (P < 0.05), the delayed memory performance after individual and WeChat health education was higher than that before education (86.9 ± 13.5) vs (80.4 ± 14.9), P < 0.05]. After individual and WeChat health education for 6 months, the decreased HbA1c value was positively correlated with the increased value of delayed memory (r = 0.353, P = 0.020) and RBANS total score (r  = 0.327, P = 0.045). Furthermore, the decreased HbA1c value was also positively correlated with the increased value of delayed memory in linear regression analysis (P < 0.05). Conclusions Individual and WeChat health education can ameliorate cognitive impairment in patients with T2DM, especially in delayed memory.