205例甲状腺结节新发患者的临床特征分析

 摘要：目的  探讨205例甲状腺结节新发患者的主要临床特征。方法  调查2015年在解放军八二医院内分泌科被诊断为甲状腺结节的205例新发患者，收集其人口学基本信息、甲状腺B超和甲状腺功能检查等资料，进行汇总分析。结果  205例甲状腺结节新发患者中，女性占86.83%（178/205）；主要患病年龄为40～59岁。甲状腺功能亢进所占比例最高，为35.12%（72/205），其次为甲状腺功能正常，占20.49%（45/205），而甲状腺功能减退最低，仅占11.22%（23/205）。男性和女性患者的直径≥1.0 cm组的促甲状腺激素（TSH）水平均高于直径<1.0 cm组，两组比较，差异有统计学意义（P <0.05）。仅女性单发结节组TSH水平高于多发结节组，两组比较，差异有统计学意义（P <0.05）。结论  单发结节和大结节的患者TSH水平较高，应及时治疗并定期进行B超和TSH复查。

Main clinical features of 205 cases of thyroid nodules

Abstract: Objective To understand the main clinical features of 205 cases of thyroid nodules. Methods A total of 205 patients of thyroid nodules were diagnosed in the Department of Endocrinology in the 82nd Hospital of PLA, and then they were surveyed. Demographic information, thyroid ultrasonograms and thyroid function of all patients were collected and analyzed. Results Among 205 cases of thyroid nodules, women accounted for 86.83% (178/205), and the main age was 40-59 years. Hyperthyroidism accounted for 35.12% (72/205), followed by the normal thyroid function (45/205, 20.49%), while hypothyroidism only accounted for 11.22% (23/205). The TSH levels of the diameter ≥1.0 cm group were higher than those of the diameter <1.0 cm group in the male and female cases (P < 0.05), and the TSH level of the single nodule group was higher than that of the multiple nodule group only in the female cases (P < 0.05). Conclusions TSH level is higher in the cases with single nodule and large nodules. Timely treatment, thyroid ultrasonography and TSH review should be carried out regularly.