| 甲状旁腺功能状态对大鼠血脂代谢的影响 |
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| 引用本文： | 陈新,杨永宗. 甲状旁腺功能状态对大鼠血脂代谢的影响[J]. 中国病理生理杂志, 1993, 0(4) |
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| 作者姓名： | 陈新 杨永宗 |
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| 作者单位： | 衡阳医学院心血管病研究所，衡阳医学院心血管病研究所 衡阳 421001，衡阳 421001 |
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| 摘 要： | 本实验通过制作SD大鼠甲状旁腺功能亢进及低下模型,观察了甲状旁腺功能状态对大鼠血脂代谢的影响。结果表明,甲状旁腺功能亢进大鼠血清TC、HDL-C及TG浓度明显升高,PHLA明显降低;而甲状旁腺功能低下大鼠血清TC、HDL-C及TG浓度则显著降低,PHLA显著升高。提示甲状旁腺功能正常为维持大鼠正常血脂代谢所必需。
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| 关 键 词： | 甲状旁腺功能亢进 甲状旁腺功能减退 脂质代谢 |
The effects of parathyroid function on lipid metabolism in rats |
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| Chen Xin,Yang Yong-Zong Institute of Cardiovascular Disease,Hengyang Medical College,Hengyang. The effects of parathyroid function on lipid metabolism in rats[J]. Chinese Journal of Pathophysiology, 1993, 0(4) |
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| Authors: | Chen Xin Yang Yong-Zong Institute of Cardiovascular Disease Hengyang Medical College Hengyang |
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| Abstract: | Hyperparathyroidism was induced by parathyroid extract iujections. Thistype of hyperparathyroidism was associated with a marked increase in serum total choles-terol (TC), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG) concentra-tions and a definite decrease in plasma postheparin lipolytic activity (PHLA). A state ofpermanent hypoparathyroidism was induced by total parathyroidectomy In the hypoparathy-roidic state, both marked decrease in serum TC, HDL-C and TG concentrations and in-crease in plasma PHLA were observed as compared with controlrats. These results indicatedthat normal parathyroid function is required for normal lipid metabolism in rats. |
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| Keywords: | Hyperparathyroidism Hypoparathyroidism Lipid metabolism |
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