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吉林省供血者人类细小病毒B19 IgG抗体的调查
引用本文:魏强,李岩,王健伟,王宏,屈建国,洪涛. 吉林省供血者人类细小病毒B19 IgG抗体的调查[J]. 中华实验和临床病毒学杂志, 2006, 20(2): 60-62
作者姓名:魏强  李岩  王健伟  王宏  屈建国  洪涛
作者单位:1. 100052,北京,中国疾病预防控制中心病毒病预防控制所
2. 吉林省血液中心
摘    要:目的 了解吉林省供血者人类细小病毒感染的流行病学情况,为评估我国B19病毒的感染状况提供基础数据.方法 用间接ELISA方法检测血清中的抗B19 IgG抗体.结果 在184份血清中,抗B19 IgG抗体总检出率为55.43%.女性抗体阳性率高于男性,差异有统计学意义(P<0.05),年龄段在35~45岁之间的献血人员抗体阳性率最高.结论 本研究数据提示吉林省地区献血人员B19病毒感染率较高,有必要进行进一步B19 DNA的调查研究,为输血安全和血液制品安全提供保障.

关 键 词:供血者  细小病毒B19,人  免疫球蛋白G
修稿时间:2006-01-10

Prevalence of anti-human parvovirus B19 IgG antibody among blood donors in Jilin province
WEI Qiang,LI Yan,WANG Jian-wei,WANG Hong,QU Jian-guo,HUNG Tao. Prevalence of anti-human parvovirus B19 IgG antibody among blood donors in Jilin province[J]. Chinese journal of experimental and clinical virology, 2006, 20(2): 60-62
Authors:WEI Qiang  LI Yan  WANG Jian-wei  WANG Hong  QU Jian-guo  HUNG Tao
Affiliation:Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China.
Abstract:Objective To investigate the prevalence of the parvovirus B19 infection among the blood donors in Jilin province to provide the basic data to evaluate the epidemics of B19 virus in China. Methods Indirect ELISA was used to detect IgG antibody against parvovirus B19 in the sera from blood donors. Results In a total of 184 serum samples, IgG antibody was detected in 55.43% samples, antibody positive rate in female was significantly higher than that in male (P<0.05) and the positive rate peaked at 35-45 years age group. Conclusion These data illustrate that the prevalence of the B19 antibody in blood donors of Jilin province was high, and it is therefore necessary to detect the B19 DNA to ensure the blood safety.
Keywords:Blood donors  Parvovirus B19   human  Immunoglobulin G
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