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检测结核抗体和腺苷脱氨酶在结核病诊断中的临床应用价值
引用本文:温志华,凌应冰,张扬立,周凤丽. 检测结核抗体和腺苷脱氨酶在结核病诊断中的临床应用价值[J]. 临床肺科杂志, 2009, 14(5): 618-619
作者姓名:温志华  凌应冰  张扬立  周凤丽
作者单位:韶关市粤北第二人民医院呼吸内科,广东,512028;韶关市粤北第二人民医院呼吸内科,广东,512028;韶关市粤北第二人民医院呼吸内科,广东,512028;韶关市粤北第二人民医院呼吸内科,广东,512028
摘    要:目的探讨联合检测结核抗体(TBAb)和腺苷脱氨酶(ADA)在结核病诊断的临床应用价值。方法对200例结核病患者进行TBAb和ADA测定,分析它们对结核病诊断的敏感性和特异性。结果结核病组血清及胸水TBAb阳性率分别是71.5%和75.8%,特异性分别是90.5%和93.3%,显著高于对照组(P〈0.01),而血清ADA阳性率低,与对照组比较则无差异;结核性胸腔积液患者的胸水ADA阳性率为88.7%,特异性为93.3%,显著高于对照组(P〈0.01)。结论测定患者血清中的TBAb和胸水中的TBAb和ADA,对结核病的诊断均有重要的临床价值,两者联合检测,并测定胸水/血清比值对结核性胸膜炎的诊断意义更大。

关 键 词:结核抗体  腺苷脱氨酶  结核病  早期诊断

TBAb and ADA testing and its significance for the diagnosis of tuberculosis
WEN Zhi-hua,LING Ying-bing,ZHANG Yang-li,ZHOU Feng-li. TBAb and ADA testing and its significance for the diagnosis of tuberculosis[J]. Journal of Clinical Pulmonary Medicine, 2009, 14(5): 618-619
Authors:WEN Zhi-hua  LING Ying-bing  ZHANG Yang-li  ZHOU Feng-li
Affiliation:(Department of Internal Medicine, the Second People's Hospital of Yuebei, Shaoguan 512028, China)
Abstract:Objective To explore the joint detection of tuberculosis antibody(TBAb) and adenosine deaminase(ADA) in the diagnosis of tuberculosis in clinical application.Methods 200 cases of tuberculosis patients using TBAb and ADA determination were studied,and the sensitivity and specificity were analyzed.Results TB in the group,serum and pleural effusion TBAb positive rate was 71.5% and 75.8%,Specificity was 90.5% and 93.3%,significantly higher(P<0.01) compared with the control group,and serum ADA-positive rate was ...
Keywords:tuberculosis antibody  adenosine deaminase  tuberculosis  early diagnosis  
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