| 亚洲人群酒渣鼻与幽门螺杆菌感染关系的Meta分析 |
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| 引用本文： | 吴淡娟,;裘宇容,;蔡翠霞.亚洲人群酒渣鼻与幽门螺杆菌感染关系的Meta分析[J].热带医学杂志,2014(6):729-732. |
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| 作者姓名： | 吴淡娟 ;裘宇容 ;蔡翠霞 |
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| 作者单位： | [1]南方医科大学南方医院检验科,广东广州510515; [2]南方医科大学基因工程研究所,广东广州510515 |
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| 摘 要： | 目的探讨亚洲人群酒渣鼻与幽门螺杆菌(Hp)感染的关系。方法用计算机检索CNKI、万方数据库、维普数据库、Pubmed、Embase等数据库,纳入关于亚洲人群幽门螺杆菌感染与酒渣鼻关系的病例对照研究。运用Stata11.0软件对文献实验数据进行Meta分析,计算比值比(OR),同时进行敏感性分析、亚组分析和Meta回归分析评估异质性来源,Begg's Test和Egger's Test评价发表偏倚。结果亚洲人群中酒渣鼻患者幽门螺杆菌感染率(77.7%)明显高于健康人群(40.0%),OR=5.82,95%CI为(3.71~9.15),P=0.000。结论幽门螺杆菌感染在酒渣鼻的发病中可能有一定的作用。
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| 关 键 词： | 酒渣鼻 幽门螺杆菌 Meta分析 |
Meta-analysis on the relationship between acne rosacea pylori infection in Asian population |
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| Institution: | WU Dan-juan, QIU Yu-rong, CAI Cui-xia( 1.Laboratory Department, Nanfang Hospital of Southern Medical University, Guangdong, Guangzhou 510515 ; 2.1nstitute of Genetic Engineering of Southern Medical University, Guangdong , Guangzhou 510515, China) |
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| Abstract: | Objective To investigate the association between acne rosacea and the infection of Helicobacter pylori（Hp）.Methods The associated case-control researches of Asia＇s acne rosacea and the infection of Hp were retrieved in the CNKI, Wan Fang Databases, the Chinese ScienceTechnology Journal Database（VIP） and Pubmed, and Meta-analysis on the experimental data by calculating the odds ratio was performed using Embase Stata11.0 software.Sensitivity analysis,subgroup analysis and Meta-regression analysis were taken to evaluate the sources of heterogeneity.Begg＇s Test and Egger＇s Test were used to evaluate publication bias. Results Infection rate of Hp in Asian patients with rosacea（77.7%） is significantly higher than healthy people（40.0%）,OR=5.82, 95% CI is（3.71-9.15）, P=0.000. Conclusion Helicobacter pylori infection may have certain effect in the pathogenesis of rosacea. |
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| Keywords: | rosacea Helicobacter pylori Meta-analysis |
| 本文献已被 CNKI 维普 等数据库收录！ |
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