宫颈癌行超选择动脉灌注栓塞介入治疗疗效的MRI分析

目的探讨MRI成像对宫颈癌超选择动脉灌注栓塞介入治疗疗效评估的临床价值。方法 20例经病理证实的宫颈癌患者在行超选择动脉灌注栓塞介入治疗前及治疗后7～14d行盆腔MRI扫描,在MRI图像上观察肿瘤在介入治疗前后的大小及信号变化。结果肿瘤完全消失6例,肿瘤体积缩小>50%10例,肿瘤体积缩小<50%4例。15例肿瘤信号消失,局部T2WI序列呈低信号,5例肿瘤信号与介入治疗前比较无明显变化。有5例肿瘤强化信号不均匀,出现"无强化区",其中4例肿瘤体积缩小<50%。15例肿瘤不强化或轻微强化,其中14例肿瘤体积缩小>50%。介入治疗后宫旁浸润肿瘤信号降低,盆腔淋巴结肿大者明显缩小。结论 MRI成像对宫颈癌超选择动脉灌注栓塞介入治疗疗效及预后评估具有重要意义。

MRI Analysis in the Evaluation of Superselective Arterial Infusion Embolization Therapy on Cervical Cancer

Objective To investigate MRI in the evaluation of superselective arterial infusion embolization therapy on cervical cancer. Methods Pelvic MRI was performed before, and at 7～14d after superselective arterial infusion embolization therapy in 20 patients with cervical cancer. The changes of carcinoma lesion in size and signal were evaluated on MR images. Results Tumor completely disappeared in 6 patients, the extent of tumor volume shrinkage was more than 50% in 10 patients and less than 50% in 4 patients. The tumor signals disappeared in 15 patients and showed hypointense signal on T2WI , 5 patients had no changes compared with before treatment. No enhancement carcinoma lesion was observed in 5 patients, the extent of tumor volume shrinkage was less than 50% in 4 patients, slight or no enhancement was observed in 15 patients, the extent of tumor volume shrinkage was more than 50% in 14 patients. After superselective arterial infusion embolization therapy, signal of parametrium tumor obvious lower, lymphoid knots contrast. Conclusion MRI imaging is helpful in evaluating cervical carcinoma response to superselective arterial infusion embolization therapy and making the therapeutic plan.