| RP—HPLC测定心脑康胶囊中2，3，5，4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的含量 |
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| 引用本文： | 杨跃龙.RP—HPLC测定心脑康胶囊中2，3，5，4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的含量[J].中国现代药物应用,2008,2(5):23-24. |
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| 作者姓名： | 杨跃龙 |
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| 作者单位： | 湖南省怀化市药品检验所,418000 |
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| 摘 要： | 目的建立心脑康胶囊中2，3，5，4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷RP—HPLC含量测定方法。方法色谱柱为Dikma C18（250mm×4．6mm，5μm）；流动相为乙腈-水（14：86）；检测波长为320nm：柱温：25℃。结果心脑康胶囊中2，3，5，4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的的线性范围为2．88—28．8μg／ml，（r=0．9999），平均回收率为99．14％，RSD值为0．3％。结论该方法简便，结果准确，可作为心脑康胶囊的质量控制方法。
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| 关 键 词： | 心脑康胶囊 2 3 5 4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷 高效液相 |
Determination the content of 2,3,5,4'-tetrahydroxyl diphenylethylene-2-O-β-D-glucoside in Xinnaokang capsule by RP-HPLC |
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| YANG Yue-long.Determination the content of 2,3,5,4''-tetrahydroxyl diphenylethylene-2-O-β-D-glucoside in Xinnaokang capsule by RP-HPLC[J].Chinese Journal of Modern Drug Application,2008,2(5):23-24. |
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| Authors: | YANG Yue-long |
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| Institution: | YANG Yue-long.( Huaihua Institute for Drug Control, Hunan, Huaihua 418000, China) |
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| Abstract: | Objective To establish a RP-HPLC method for determination the content of 2,3,5,4＇ -tetrabydroxyl diphenylethylene-2-O-β-D-glucoside in Xinnaokang capsule. Methods The Dikma C18 column（250 mm × 4. 6 mm, 5 μm） was used, The acetonitrile-water （ 14 ： 86 ） as mobile phase, the flow rate was 1.0 ml· min^-1, the detection wavelength was 320 nm. Results The linear ranges of 2,3,5,4 ＇ -tetrahydroxyl diphenylethylene-2-O-β-D-glucoside was at 2.88-28.8 μg/ml, the average recoveries （ n = 5） was 99.14%. with RSD 0. 3%. Conclusion The method is simple and accurate, it can be used for quality control method of Xinnaokang capsule. |
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| Keywords: | Xinnaokang capsule 2 3 5 4＇ -tetrabydroxyl diphenylethylene-2-O-β-D-glucoside HPLC |
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