小牛血去蛋白提取物眼用凝胶在角膜异物剔除术后的应用

目的:探讨小牛血去蛋白提取物眼用凝胶在角膜异物剔除术后应用的临床疗效.方法:角膜异物104例104眼按照治疗方式不同分组:治疗组55例55眼、对照组49例49眼.对照组患者术后给予洛美沙星滴眼液、氧氟沙星滴眼液,治疗组在对照组治疗基础上给予小牛血去蛋白提取物眼凝胶.结果:治疗后1、2wk,治疗组总有效率分别为85.5％、96.4％,均分别高于对照组的总有效率,差异有统计学意义(P＜0.01).治疗组症状体征综合积分在治疗后1、2wk分别为4.82±2.18、1.65±2.21分,均低于对照组,差异有统计学意义(P＜0.01).结论:角膜异物剔除术后应用小牛血去蛋白提取物眼凝胶可加快上皮修复,安全有效.

Effect of deproteinized calf blood extract eye gel for corneal epithelial repair after corneal foreign body removal surgery

AIM: To investigate the clinical efficacy of deproteinized calf blood extract eye gel in the treatment of corneal foreign body.

METHODS: One hundred and four cases(104 eyes)with corneal foreign body were divided into two groups according to different treatment methods: treatment group(55 eyes)and control group(49 eyes). In the control group, the postoperative dropped lomefloxacin eye drops and ofloxacin eye ointment. On the basis of control, the treatment group combined with deproteinized calf blood protein extract eye gel.

RESULTS: The total effective rate of the treatment group after 1wk, 2wk were 85.5%,96.4% higher than that of control group. The difference was statistically significant(P<0.01). The symptoms and signs of the treatment group after 1wk of treatment were 4.82±2.18 score, 2wk after treatment were 1.65±2.21 score, and were lower than control group(P<0.01).

CONCLUSION: Deproteinized calf blood extract eye gel can accelerate epithelial repair. It is safe and effective after removal of foreign body from corneal foreign body.