断血流颗粒联合米索前列醇治疗剖宫产后出血的疗效观察

目的探讨断血流颗粒联合米索前列醇治疗剖宫产后出血的临床疗效。方法选取2015年1月—2016年1月在安塞县人民医院接受治疗的产后出血患者86例,随机分组法分为对照组和治疗组,每组各43例。对照组直肠给予米索前列醇片,0.2 g/次。治疗组在对照组基础上口服断血流颗粒,1袋/次,3次/d。观察两组的临床疗效,比较两组产后出血、宫缩、血红蛋白(Hb)和红细胞压积(HCT)的情况。结果治疗后,对照组和治疗组的总有效率分别为86.05%、97.67%,两组比较差异有统计学意义(P0.05)。治疗2、24 h后,两组产后出血明显下降,同组治疗前后比较差异有统计学意义(P0.05);且治疗组这些观察指标的下降程度明显优于对照组,两组比较差异具有统计学意义(P0.05)。治疗后,与对照组比较,治疗组宫缩恢复时间明显缩短,两组比较差异具有统计学意义(P0.05)。治疗后,两组Hb和HCT均明显升高,同组治疗前后比较差异有统计学意义(P0.05);且治疗组这些观察指标的升高程度明显优于对照组,两组比较差异具有统计学意义(P0.05)。结论断血流颗粒联合米索前列醇治疗剖宫产后出血具有较好的疗效,可减少产后出血,改善子宫收缩功能,具有一定的临床推广应用价值。

Clinical observation of Duanxueliu Granules combined with misoprostol in treatment of postpartum hemorrhage of cesarean section

Objective To investigate the clinical effect of Duanxueliu Granules combined with misoprostol in treatment of postpartum hemorrhage of cesarean section. Methods Patients (86 cases) with postpartum hemorrhage of cesarean section in Ansai County People''s Hospital from January 2015 to January 2016 were randomly divided into the control and treatment groups, and each group had 43 cases. Patients in the control group were rectal administered with Misoprostol Tablets, 0.2 mg/time. Patients in the treatment group were po administered with Duanxueliu Granules on the basis of the control group, 1 bag/time, three times daily. After treatment, the clinical efficacies were evaluated, and postpartum hemorrhage, uterine contraction, Hb, and HCT in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 86.05% and 97.67%, respectively, and there was difference between two groups (P<0.05). After 2 h and 24 h treatment, the postpartum hemorrhage in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the recovery time of uterine contraction in the treatment group was shorter than that in the control group, and there was difference between two groups (P<0.05). After treatment, Hb and HCT in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). Conclusion Duanxueliu Granules combined with misoprostol has clinical curative effect in treatment of postpartum hemorrhage of cesarean section, and can reduce postpartum hemorrhage, improve uterine contraction function, which has a certain clinical application value.