1例白蛋白结合型紫杉醇致重度骨髓抑制合并肺部感染的药学服务

摘 要 目的：为临床药师对化疗药物引起的重度骨髓抑制合并感染患者的药学监护提供参考。方法: 临床药师参与1例胆管癌术后复发患者化疗后重度骨髓抑制合并肺部感染的监护过程。从化疗方案的评估、骨髓抑制的对症治疗、骨髓抑制后的抗感染治疗等方面提出药物建议。 结果: 患者骨髓抑制得以缓解，肺部感染好转，未发生其他严重不良反应。结论:临床药师通过提供个体化用药方案，提高了重度骨髓抑制患者的治疗效果及用药安全性。

Pharmaceutical Care for One Patient with Severe Bone Marrow Suppression Complicated with Pulmonary Infection Induced by Albumin Bound Paclitaxel

ABSTRACT Objective: To provide reference for clinical pharmacist in the treatment of severe bone marrow suppression complicated with infection induced by chemotherapeutic drugs. Methods: The pharmaceutical care was performed by clinical pharmacist for a patient with severe bone marrow suppression complicated with pulmonary infection caused by chemotherapy. The suggestions on the drug use in the evaluation of chemotherapy regimen and the treatment of bone marrow suppression and infection were provided. Results:The bone marrow inhibition was relieved, the pulmonary infection was improved, and no other severe adverse reactions were shown. Conclusion:Clinical pharmacist can improve effectiveness and safety in the treatment of patients with severe bone marrow suppression by providing individualized drug treatment.