活血化瘀法为主治疗慢性丙型肝炎的临床研究

临床比较观察活血化瘀为主的中药组(15例)与干扰素组(15例)治疗慢性丙型病毒性肝炎的疗效.结果发现中药组与干扰素组对HCV-RNA的转阴率均为20.00%,抗HCV的转阴率分别为33.33%和26.66%;在症状、肝功能的改善方面,中药组明显优于干扰素组,干扰素组存在不同程度的不良反应.中药组抗病毒远期疗效与干扰素组比较更为稳定持久,具有统计学意义.病理检测结果证实中药组有改善肝细胞充血水肿、汇管区的炎症细胞浸润和肝细胞坏死的作用.

Chnical Research of Chronic Hepatitis C Treated Mainly by Blood-Activating and Stasis-Resolving Therapy

In the clinical comparison and observation of the therapeutic effect in the treatment of chronic hepatitis C in Chinese medicine group by the blood activating and stasis resolving method(15 cases)and in the interferon group(15 cases),the results showed that the negative transferring rate of HCV TNA was 20.00% in both Chinese medicine group and interferon group,the negative transferring rate of anti HCV was respectively 33.33% and 26.66%,the improvement of the symptoms and liver functions was obviously better in Chinese medicine group than in the interferon group and that bad reaction in various degrees existed in the interferon group.In comparison with the interferon group,the long term anti virus effect was more stable and persistent statistically in Chinese medicine group.It was proved in the pathological examinations that Chinese medicine could abate edema and congestion of liver cell,infiltration of inflammatory cell in the portal area and necrosis of liver cell.