| 异丙酚对兔离体气管平滑肌收缩力的影响 |
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| 引用本文： | 傅诚章,周钦海,钱燕宁,刘存明,丁正年.异丙酚对兔离体气管平滑肌收缩力的影响[J].临床麻醉学杂志,2001,17(4):209-210. |
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| 作者姓名： | 傅诚章 周钦海 钱燕宁 刘存明 丁正年 |
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| 作者单位： | 南京医科大学第一附属医院麻醉科 |
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| 摘 要： | 目的 探讨异丙酚对气管平滑肌的直接影响，为有气管高反应患者临床选择用药提供实验参考依据。方法 采用电刺激兔离体气管平滑肌的方法研究异丙酚对其的影响。结果 10^-4mol/L的异丙酚可使电刺激诱发的兔离体气管平滑肌收缩力下降21．6％，10^-2mol/L的异丙酚可使电刺激诱发的兔离体气管平同收缩力下降35．4％。结论 异丙酚有舒张兔离体气管平滑肌的作用。
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| 关 键 词： | 异丙酚 气管平滑肌 电刺激 收缩力 兔 气管高反应 |
| 修稿时间： | 2000年6月24日 |
Effect of propofol on contraction of isolated rabbit tracheal smooth muscle |
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| Fu Chengzhang,Zhou Qinhai,Qian Yanning,et al..Effect of propofol on contraction of isolated rabbit tracheal smooth muscle[J].The Journal of Clinical Anesthesiology,2001,17(4):209-210. |
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| Authors: | Fu Chengzhang Zhou Qinhai Qian Yanning |
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| Institution: | Fu Chengzhang,Zhou Qinhai,Qian Yanning,et al.Department of Anesthesiology,First Affiliated Hospital,Nanjing Medical University,Nanjing 210029 CHINA |
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| Abstract: | Objective To explore the direct effect of propofol on the isolated tracheal smooth muscle for providing an useful information during choosing drug in the patients with airway hyperreactivity.Methods Electrical field stimulation was used to induce the isolated rabbit tracheal smooth muscle tension.Results 10 -4mmol/L and 10 -2mmol/L propofol reduced isolated rabbit tracheal smooth muscle tension induced by the electrical field by 21.6% and 35.4% respectively.Conclusion Propofol has an effect of relaxing the isolated tracheal smooth muscle. |
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| Keywords: | Propofol Tracheal smooth muscle Electrical field stimulation |
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