Immunomodulation of murine collagen-induced arthritis by N,N-dimethylglycine and a preparation of Perna canaliculus |
| |
| Authors: | Brian R Lawson Stanley M Belkowski John F Whitesides Paul Davis John W Lawson |
| |
| Affiliation: | (1) Department of Biological Sciences, Clemson University, Clemson, SC, USA;(2) Department of Animal and Veterinary Sciences, Clemson University, Clemson, SC, USA;(3) Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand |
| |
| Abstract: | Background Rheumatoid arthritis (RA) and its accepted animal model, murine collagen-induced arthritis (CIA), are classic autoimmune inflammatory diseases which require proinflammatory cytokine production for pathogenesis. We and others have previously used N, N-dimethylglycine (DMG) and extracts from the New Zealand green-lipped mussel Perna canaliculus (Perna) as potent immunomodulators to modify ongoing immune and/or inflammatory responses. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
