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重型乙型肝炎患者TNF和IL-1的检测及意义
引用本文:彭齐荣,李奇芬,王宇明.重型乙型肝炎患者TNF和IL-1的检测及意义[J].免疫学杂志,1994(2).
作者姓名:彭齐荣  李奇芬  王宇明
作者单位:第三军医大学西南医院传染科,广州空军医院肝病研究所
摘    要:检测30例重型乙型病毒性肝炎(重型肝炎)患者血清和外周血单个核细胞(PBMC)培养上清中肿瘤坏死因子(TNF)水平及PBMC诱生的白细胞介素1(IL-1)活性,结果:重型肝炎患者TNP和IL-1水平均增高,且二者呈正相关。提示TNF和IL-1在重型肝炎的发病机制中起重要作用。

关 键 词:重型乙型病毒性肝炎,TNF,IL-1

Tbe Detection and Its Significance of TNF and IL-1 in Patientswith Severe Hepatitus B
Peng Qirong,Li Qifeng,Wang Yuming.Tbe Detection and Its Significance of TNF and IL-1 in Patientswith Severe Hepatitus B[J].Immunological Journal,1994(2).
Authors:Peng Qirong  Li Qifeng  Wang Yuming
Abstract:The ievels of Tumor Necrosis Factor( TNF ) and lnterleukin-1(IL-1) in serum and cuture supernate ofperpherd blood mononuclear cells wer measured in thirty patients with severe hepatitis B.The results showed that the level of TNF and IL-1 in patent wer increased remarkably.This suggested that TNF and IL-1may play an important role in patogenesis of severe hepatitis B
Keywords:Severe viralhepatiti B  TNF  IL-1  
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