杜氏手法结合臭氧注射治疗膝骨关节炎的临床研究

目的探讨单用手法治疗与杜氏手法配合关节腔臭氧(O3)注射治疗膝骨关节炎的疗效。方法选择确诊的膝骨关节炎患者60例,分为手法治疗组和手法加O3关节腔注射治疗组(关节腔注射治疗组)。手法治疗组予以杜氏手法,每次20min,每周2次;关节腔注射治疗组在手法治疗组治疗基础上予以关节腔注射浓度为40μg/ml的O31次/周,20 ml/次,疗程均为20周。通过疼痛视觉模拟评分(VAS)、膝关节功能评分(HSS)、关节软骨缺损评分(Noyes)来评价疗效。结果研究中发现每组治疗前后VAS评分、HSS评分、Noyes评分自身比较差异有统计学意义(P<0.05)。2组治疗后组间比较:VAS评分手法治疗组(3.18±0.76)分,关节腔注射治疗组(2.62±0.55)分,差异有统计学意义(P<0.05);HSS评分2组比较差异无统计学意义(P>0.05);Noyes评分手法治疗组治疗后(3.32±0.98)分,关节腔注射治疗组治疗后(2.79±1.2)分,差异有统计学意义(P<0.05)。结论研究中单纯手法治疗和手法配合关节腔O3注射治疗膝骨关节炎均有良好效果,手法配合关节腔O3注射在疼痛控制和促进关节软骨修复方面较单纯手法治疗效果好,值得进一步研究应用。

Clinical study of knee osteoarthritis by manipulation combined with ozone injection

Objective To study efficacy of knee osteoarthritis treatment by single manipulation therapy and manipulation therapy with ozone injection in joint cavity.Methods Selected 60 cases of knee osteoarthritis patients randomized divided into manipulation therapy group(A group) and manipulation therapy group with ozone injection in joint cavity group(B group).Group A applied Donovani manipulation method,each time 20min,weekly 2 times.Group B applied manipulation therapy with ozone injection in articular cavity 40μg/ml once a week,20ml/each time,course of treatment 20 weeks.Evaluation of through VAS score,HSS score and Noyes loss of joint cartilage score.Results There was a self compared significant differences in pre and post therapy of each group by VAS score,HSS score,Noyes loss of joint cartilage score(P<0.05).VAS score in group A was 3.18±0.76 and was 2.62±0.55 in group B.There was a significant differences between two groups(P<0.05).There was no significant differences in HSS score between two groups(P>0.05).Group A of post treatment of Noyes loss of joint cartilage score was 3.32±0.98,and group B was 2.79±1.2.There was a significant differences(P<0.05).Conclusion There is an effective result in single manipulation therapy and manipulation therapy with ozone injection in joint cavity.There is a treatment effectiveness of manipulation therapy with ozone injection in joint cavity than single manipulation therapy in pain control and promotion of compound joint cartilage repair and worth for further study.