Effect of hypothermia on renal sodium reabsorption |
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| Authors: | Giorgio Torelli Eloisa Milla Leonard I Kleinman Alide Faelli |
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| Institution: | (1) Istituto di Fisiologia Generale, Università di Milano, Italia;(2) Present address: Kettering Laboratory, University of Cincinnati Medical School, Cincinnati, Ohio, (U.S.A.) |
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| Abstract: | Summary The relationship between sodium reabsorption and oxygen consumption was studied in an isolated rabbit kidney preparation perfused with blood at 37, 28 and 19° C. When the temperature was lowered from 37° C to 28° C and to 19°C the rate of oxygen consumption and of the maximal P.A.H. excretion (Tm P.A.H.) decreased more than that of sodium reabsorption.TheQ
10 for sodium reabsorption is about 1.8, while that for maximal P.A.H. excretion is 2.5. Some hypothesis on the possible mechanisms of the lowQ
10 of the Na+ reabsorption are forwarded.Preliminary reports have been published Boll. Soc. Ital. Biol. Sper.43, 1019–1023 (1966) and44, 1784–1787 (1967);45, 860–862 (1969) and45, 863–865 (1969)]. |
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| Keywords: | Tubular Na+ Reabsorption O2 Consumption in Kidney: Na/O2 Tubular Ratio Passive Sodium Transport Renal Hypothermia P A H Excretion |
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