Methsuximide for intractable childhood seizures |
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| Authors: | M B Tennison R S Greenwood M V Miles |
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| Affiliation: | Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill 27599-7025. |
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| Abstract: | Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy. In 15 patients the drug was well tolerated and resulted in a 50% or greater reduction in seizure frequency. No serious or irreversible adverse effects were seen. Methsuximide is frequently overlooked and may be an effective adjunctive antiepileptic for children with intractable seizures. |
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