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| 克拉霉素干混悬剂体外抗菌活性的研究 | |
| 引用本文： | 朱莲娜,林军,黄万清,吴晓宁. 克拉霉素干混悬剂体外抗菌活性的研究[J]. 广西医科大学学报, 1999, 16(1): 29-32 |
| 作者姓名： | 朱莲娜 林军 黄万清 吴晓宁 |
| 作者单位： | 1. 广西医科大学第一附属医院检验科,南宁,530021 2. 广西医科大学药理学研究室 3. 南宁武警总医院检验科 |
| 摘 要： | 目的：探讨克拉霉素新剂型－－干混悬剂的体外抗菌作用。方法：应用稀释法及临床分离所得的２８５株致病菌对克拉霉素干 阳性对照药红霉素进行外抗菌活性的测定，并考查了细菌接种量，血清浓度和培养基Ｐ至克拉霉素干混悬剂最小抑菌浓度（ＭＩＣ）的影响，同时测出受度药克 霉素干混悬剂的 |
| 关 键 词： | 克拉霉素 干混悬剂 体外抗菌活性 |
| 修稿时间： | 1998-01-08 |
THE STUDY ON IN VITRO ANTIBACTERIAL ACTIVITY OF CLARITHROM-YCIN DRIED SUSPERISON |
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| Zhu Lianna, Lin Jun, Huang Wanqing, et al. THE STUDY ON IN VITRO ANTIBACTERIAL ACTIVITY OF CLARITHROM-YCIN DRIED SUSPERISON[J]. Journal of Guangxi Medical University, 1999, 16(1): 29-32 | |
| Authors: | Zhu Lianna Lin Jun Huang Wanqing et al |
| Abstract: | In order to observe the in vitro antibactrial activites of clarithromycin dried suspension and erythromycin. Methods: The drugs against 285 clinical isolates were studied by the diluting method. The differ-ent on quantum of bacteria, serum concentration and pH of culture medium were also detected. Results: The re-sults indicated that the in vitro activity of clarithromycin dried suspension was the same as erythromycin. Both of the drugs are effective against erythromycin-sensitive Staph. spp. and Strep. spp. (MIC90 0. 125 mg/ml), and had also some effect on erythromycin-resistant bacteria. But there was no effect on Esch. coli and Kleb. p-neumoinae. The action of clarithromycin dried suspension was strong when pH was 8. 0, but was repressed when serum concentration was >75 %. Conclusion: The clarithromycin dried suspenaion is a new drug against bacteri a, and its antibacterial activity has been fully proved. |
| Keywords: | clarithromycini dried suspension in vitro antibacterial activity |
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