E-Flow成像对鼻咽癌颈转移淋巴结放疗疗效评估

目的：探讨E-Flow成像评估鼻咽癌颈部转移淋巴结放疗疗效价值。方法：对52例鼻咽癌伴颈部转移淋巴结的初发患者采用放射治疗，在放疗前后应用二维超声和E-Flow成像观察颈部转移淋巴结大小、血流动力学参数及血流丰富程度。分析颈转移淋巴结大小、血流动力学参数、血流丰富程度与放疗疗效的关系。结果：鼻咽癌颈淋巴结转移灶放疗前共计94枚，放疗后40枚淋巴结消失， 52枚缩小，2枚大小不变。所有残留淋巴结血流减少或消失，淋巴结内动脉血流频谱由高速高阻变为低速低阻。临床疗效与颈转移淋巴结放疗前大小及血流丰富程度相关（P<0.05）。结论：E-Flow成像技术可观测放疗前后鼻咽癌颈部转移淋巴结的大小及血供变化，对放疗疗效评估有重要作用。

Radiotherapy efficacy of E-Flow imaging on cervical lymph nodes metastasized from nasopharyngeal carcinoma

Objective To explore the effect of E-Flow imaging on the radiotherapy of cervical lymph nodes metastasized from nasopharyngeal carcinoma.Methods A total of 52 nasopharyngeal carcinoma patients with 94 invasion neck lymph nodes were treated with conventional radiotherapy. Lymph node size, hemodynamic parameters, and blood supply were detected by E-Flow imaging and two-dimensional ultrasound before and after the radiotherapy. The relationship between those examinations and radiotherapy effect was analyzed.Results Of the 94 metastatic cervical lymph nodes from nasopharyngeal carcinoma before the radiotherapy, 40 disappeared, 52 reduced, and 2 maintained the original size after the radiotherapy. Blood flow in all residual lymph nodes decreased or disappearaed. Artery flow spectrum in the lymph node was changed from the high-speed high impedance to low-speed low resistance. The size of cervical lymph node and blood flow before the radiotherapy were associated with clinical efficacy (P<0.05). Conclusion E-Flow imaging plays an important role in assessing the efficacy of radiation therapy by changing the blood supply of cervical lymph node and its size before and after the radiotherapy.