慢性阻塞性肺疾病患者血清IL-6、IL-8、高敏C反应蛋白、甲状腺激素水平变化的临床研究

目的 探讨慢性阻塞性肺疾病(COPD)患者血清白介素6(IL-6)、IL-8、高敏C反应蛋白、甲状腺激素水平变化.方法 将60例COPD患者作为观察组,采用酶联免疫法测定血清IL-6、IL-8、高敏C反应蛋白、甲状腺激素水平,选择60例健康查体者为对照组.对两数据进行统计学分析.结果 观察组血清IL-6、IL-8以及甲状腺激素水平均明显高于对照组;观察组高敏C反应蛋白水平低于对照组,差异均有统计学意义(P＜0.05).结论 血清IL-6、IL-8、高敏C反应蛋白、甲状腺激素水平在COPD的发病中起重要作用,与机体的系统性炎症有密切关系.

COPD Patients Blood Serum IL-6,IL-8,High-sensitivity C-reactive Protein,Thyroxin Level Change Clinical Research

Objective Explore COPD patients blood serum IL-6,IL-8,C-reactive protein,thyroxin level change.Methods Taken the observation group 60 example COPD patients,used enzyme association immunity law determination blood serum IL-6,IL-8,C-reactive protein,thyroxin levels,choosed 60 example healthy persons physical examination to made the control group.Carried on statistics analysis to two data.Results Observation group blood serum IL-6,IL-8,as well as thyroxin levels,obviously were higher than the control group.The observation group C-reactive protein level was lower than the control group.Two groups of comparisons,the difference had statistics significance(P<0.05).Conclusion Blood serum IL-6,IL-8,C-reactive protein,thyroxin levels in the COPD morbidity the vital role,inflammatory have the close relation with organism systematic characteristic.