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主动脉夹层与高尿酸血症相关性研究
引用本文:代玉川,李传方,张猛,甘立军,郭军霞. 主动脉夹层与高尿酸血症相关性研究[J]. 实用心脑肺血管病杂志, 2012, 20(4): 592-593
作者姓名:代玉川  李传方  张猛  甘立军  郭军霞
作者单位:1. 济宁医学院附属医院,山东省心脏疾病重点实验室,山东省济宁市,272029
2. 山东大学医学院
摘    要:目的应用病例对照研究方法探讨主动脉夹层与高尿酸血症的相关性,进一步从临床生化角度探讨主动脉夹层形成的可能原因,并提出防治措施。方法选取经增强CT或MRI确诊为主动脉夹层患者179例作为病例组,对照组为同一医院同期相同年龄段住院的非主动脉夹层患者183例。收集患者的一般资料及血尿酸指标,采用相关危险因子及t检验、χ2检验研究其相关性。结果血尿酸与主动脉夹层的联系强度高〔OR=3.26,95%CI(2.01,4.78)〕,说明高尿酸血症者发生主动脉夹层的危险性是血尿酸正常者的3.26倍。结论高尿酸血症是主动脉夹层的危险因子,两者存在明显的相关性。

关 键 词:主动脉疾病  高尿酸血症  预防

Aortic Dissection Associated with Hyperuricemia Research
Affiliation:DAI Yu-chuan,LI Chuan-fang,ZHANG Meng,et al.Affiliated Hospital of Jining Medical College,Shandong Provinical Key Laboratory of Cardiac Disease Diagnosis and Treatment,Jining 272029,China
Abstract:Objective A case-control study was used to probe into the relationship between aortic dissection and hyperuricemia,further clinical from the perspective between the possible causes of aortic dissection,and proposed control measures.Probing into the possible cause of aortic dissection further in the clinical biochemistry in dicators and providing some therapyand prevention measures.Methods Select by enhanced CT or MRI confirmed 179 cases of aortic dissection patients as case group and control group for the same period in the same hospital the same age non-hospitalized patients with 183 cases of aortic dissection.Collection of patient data and blood uric acid of the general indicators,using the relevant risk factors and T-test,chi-square test of its relevance.Results Serum uric acid and aortic dissection contact strength(OR)= 3.26,shows the occurrence of hyperuricemia are risk of aortic dissection is a normal serum uric acid of 3.26 times.Conclusion Hyperuricemia is a risk factor for aortic dissection,there is a clear correlation between the two.
Keywords:Aortic diseases  Hyperuricemia  Prevention
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