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血清脂联素、抵抗素与冠状动脉病变程度的相关性研究
引用本文:朱豪,巢毅,徐尚华. 血清脂联素、抵抗素与冠状动脉病变程度的相关性研究[J]. 实用心脑肺血管病杂志, 2012, 20(4): 599-600
作者姓名:朱豪  巢毅  徐尚华
作者单位:福建医科大学附属南平第一医院心内科,福建省南平市,353000
摘    要:目的 测定冠心病患者血清脂联素(APN)、血清抵抗素(FSR),探讨二者与冠状动脉病变程度的关系.方法 将138 例进行冠状动脉造影检查的疑诊冠心病患者分为正常对照组、单支病变组、双支病变组和多支病变组.应用自动生化仪测定空腹血糖、高敏C反应蛋白(hsCRP),ELISA 法测定血清APN、FSR.结果 冠心病患者各亚组随着冠状动脉病变程度的增加,FSR增加,APN 水平下降.结论 血清 APN 和FSR与冠状动脉病变程度密切相关.

关 键 词:冠状动脉疾病  脂联素  抵抗素

Relationship among Severity of Coronary Artery Pathologies Serum Adiponectin and Resistin in Coronary Heart Disease Patients
ZHU Hao , CHAO Yi , XU Shang-hua. Relationship among Severity of Coronary Artery Pathologies Serum Adiponectin and Resistin in Coronary Heart Disease Patients[J]. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease, 2012, 20(4): 599-600
Authors:ZHU Hao    CHAO Yi    XU Shang-hua
Affiliation:.Department of Cardiology,Affiliated Nanping First Hospital of Fujian Medical University,Nanping 353000,China
Abstract:Objective To investigate the relationship among severity of coronary artery pathologies,serum adiponectin(APN)and resistin(FSR)in coronary heart disease(CHD)patients.Methods One hundred and thirty seven patients with suspected CHD undergoing coronary angiographies were divided to no vessel pathology group,single vessel pathology group,double vessel pathologies group and multiple vessel pathologies group.Measuring fasting blood glucose serum,high sensitivity C-reactive protein(hsCRP)by automatic biochemical analyzer,measuring APN and FSR by ELISA.Results There were no significant difference of the above items among four groups.With deterioration of the severity of coronary artery pathologies hsCRP and FSR were increased and APN was declined.Conclusion Serum APN and FSR were closely related to CHD.
Keywords:Coronary heart disease  Adiponectin  Resistin
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