| 反复上呼吸道感染T细胞亚群特点及与球蛋白的相关性 |
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| 引用本文： | 谭国平,陈桂良.反复上呼吸道感染T细胞亚群特点及与球蛋白的相关性[J].现代医院,2011,11(12):5-7. |
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| 作者姓名： | 谭国平 陈桂良 |
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| 作者单位： | 1. 茂名石化医院,广东茂名,525000
2. 东莞市长安医院,广东东莞,523843 |
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| 摘 要： | 目的探讨反复上呼吸道感染(FURI)患者的细胞及体液免疫特征。方法收集现症及恢复期FURI患者各28例,选取健康体检者20例作为对照;用流式细胞术检测外周血CD4CD45RA及CD4CD45RO T细胞亚群的含量;运用速度散射比浊法测定IgG、IgA及IgM的含量;将T细胞亚群及Ig数量进行相关性分析。结果以上两组CD4CD45RA的变化趋势为现症组<恢复组<健康组(F=3.541,p=0.002),而CD4CD45RO为现症组>恢复组>健康组(F=3.612,p=0.001);IgG及IgA的变化趋势为:现症组<恢复组<健康组(F=3.023,p=0.012;F=2.862,p=0.018),IgM的组间变化趋势是:现症组>恢复组>健康组(F=2.592,p=0.026);相关性分析显示CD4CD45RA与CD4CD45RO呈显著负相关性,CD4CD45RO与IgM呈正相关性,CD4CD45RA与IgG及IgA均呈显著正相关性(均为p<0.05)。结论以CD4CD45RA/CD4CD45RO为代表的细胞免疫及以Ig为代表的体液免疫在URI发病及转归中发挥重要作用。
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| 关 键 词： | 上呼吸道感染 T细胞亚群 免疫球蛋白 免疫平衡 相关性分析 |
CORRELATION OF T CELL SUBSETS WITH IMMUNE GLOBULINS IN PATIENTS WITH FREQUENT UPPER RESPIRATORY TRACT INFECTION |
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| TAN Guoping,CHEN Guiliang.CORRELATION OF T CELL SUBSETS WITH IMMUNE GLOBULINS IN PATIENTS WITH FREQUENT UPPER RESPIRATORY TRACT INFECTION[J].Modern Hospital,2011,11(12):5-7. |
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| Authors: | TAN Guoping CHEN Guiliang |
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| Institution: | TAN Guoping,CHEN Guiliang The Petrochemial Hospital of Maoming City,Guangdong Province 525000 PRC |
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| Abstract: | Objective To investigate the characteristics of cell immunity and humoral immunity in patients with frequent upper respiratory tract infection(FURI). Methods 28 patients belonging to current acute infection,28 ones of convalescence and another 20 healthy people for routine examination were enrolled in our study(stated as group A,B and C).The T cell subsets ratios of CD4CD45RA and CD4CD45RO were detected through flow cytometry.The quantity of IgG,IgA and IgM were determined by rate nephelometry.Pearson analy... |
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| Keywords: | Upper respiratory tract infection T cell subsets Immune globulins Immunologic balance Correlation analysis |
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