长脉冲1064nm Gentle YAG激光联合595nm脉冲染料激光治疗增厚型微静脉畸形回顾性分析

目的：观察长脉冲1064nm Gentle YAG激光联合595nm脉冲染料激光治疗增厚型微静脉畸形的临床疗效和不良反应。方法：使用长脉冲1064nm Gentle YAG激光和595nm脉冲染料激光对14例患者进行治疗,其中长脉冲1064nm Gentle YAG激光能量密度150～240J/cm2,光斑直径3mm,脉宽20～40ms;595nm脉冲染料激光能量密度12～15J/cm2,光斑直径7mm,脉宽6～20ms;共治疗2～7次,间隔时间4～8周。结果：痊愈6例（6/14）,显效5例（5/14）,好转3例（3/14）,无效0例。治疗后出现轻度色素沉着3例（3/14）,均在数月后恢复,遗留增生性瘢痕1例（1/14）,凹陷性瘢痕1例（1/14）。结论：长脉冲1064nm Gentle YAG激光联合595nm脉冲染料激光是目前比较安全、高效的治疗增厚型微静脉畸形的方法。

Retrospective study of long-pulsed 1064nm Gentle YAG laser combined with 595nm pulsed dye laser in the treatment of the type of thickening mico-Venous malformation

Objective To study the clinic effects and adverse reaction of long pulsed 1064nm gentle YAG laser combined with 595nm pulsed dye laser in the treatment of thickening micro-venous malformation. Methods Totally 14 patients were treated by long-pulsed 1064nm gentle YAG laser and 595nm pulsed dye laser, Correlated parameters as follows：long-pulsed 1064 nm gentle YAG laser with 20～40ms pulse width and 3mm spot diameter. The energy density used from 150～240J/cm2. 595nm pulsed dye laser with 6～20ms pulse width and 7mm spot diameter. The energy densityused from12～15J/cm2. Observed the therapeutic effect and side effects after 3～8 treatment times, the interval time is 4～8 weeks. Results 6 cases （6/14） gained complete healing, 5 cases （5/14） gained marked effect, 3 cases （3/14） gained effective therapy, 0 cases was ineffective. There are 3 cases （3/14） with light pigmentation after the course oftreatment, but it can recover in several months, depressed scar were remained in 1 patient （1/14）, 1 patient （1/14）showed hyperplastic scar. Conclusion Combined two kinds of laser is higher effective and safe method for the treatment of thickening micro-venous malformation.