肝移植受者生存质量及其影响因素研究

目的 研究肝移植受者的生存质量及其影响因素,为提高其生存质量,提供科学依据.方法 采用SF-36、SAS、SDS及社会支持评定量表分别对术前33例等待肝移植的终末期肝病患者(术前组)和肝移植术后2周以上住院患者及门诊随访者102例(术后组)进行问卷调查.结果 2组SF-36得分除生理机能、情感职能及社会功能3个维度外,其余5个维度得分及SF-36总分术后组均显著高于术前组;术后1年以上受者的生存质量优于1年以内的受者.生存质量的影响因素为主观支持和焦虑.结论 肝移植术后患者的生存质量明显改善;术后1年以上受者的生存质量优于术后1年以内的受者;生存质量与主观支持呈正相关,与焦虑呈负相关.

Investigation of quality of life and its influencing factors of the patients after liver transplantation

Objective To investigate the quality of life and its influencing factors in hver transplantation recipients in order to supply scientific reference for improving their life quality.Methods 33 patients with terminal liver diseases waiting for liver transplantation(the pre-operation group)and 102 patients 2 weeks after liver transplantation and outpatients for follow-up visits(the post-operation group)were conducted with SF-36,self-rating anxiety scale,self-rating depression scale,and social support questionnaire.Results Except for the scores of physiological function,emotional role,social function in SF-36.differences of scores of other factors were evident between the preand post-operation groups.Life quality of patients over 1 year after operation was better than those within 1 year. The influencing factors of QOL were subjective support and anxiety.Conclusions After liver transplantation,the patients' QOL evidently improves.Life quality of patients over 1 year after operation was better than those within 1 year.Patients' QOL is positively related to subjective support,negatively related to anxiety.