不同浓度的七氟醚在小儿麻醉诱导过程中疗效的观察

目的比较不同浓度的七氟醚在小儿麻醉中效果、不良反应、苏醒质量和安全性的差别。方法将60例3～12岁实施手术治疗的患儿随机分为A、B、C三组，每组各20例，分别用4％、8％、12％七氟醚进行麻醉诱导，连续检测呼吸循环等相关参数，记录麻醉效果、不良反应、术后苏醒时间及复合氯胺酮用量。结果B组与A、C组比较诱导平稳（P〈0．05），氯胺酮的复合用量明显低于A、C组（P〈0．05），术后躁动等不良反应少于A、C组（P〈0．05），术后苏醒时间差异无统计学意义。结论8％七氟醚用于小儿麻醉诱导时，诱导快、无异味刺激，对循环呼吸影响小，术后并发症如恶心、呕吐、兴奋躁动等发生率低，是应用于小儿麻醉诱导的理想浓度。

Observation curative effect of different concentration sevoflurane during induction in pediatric anesthesia

Objective To compare the effect, side effects, recovery quality and safety of different concentration of sevoflurane in pediatric anesthesia. Methods Randomly divided 60 cases from 3 to 12 years old treated by surgery into A, B and C group, respectively induced in 4%, 8%, and 12% sevoflurane, continuously detected parameters of respiratory and circulatory system, recorded the anesthesia effect, adverse reactions, recovering time and dosage of composite ketamine. Resuits Group B got more stable induction, less dosage of composite ketamine, and less adverse reactions such as postoperative restlessness, than group A and C （ P 〈 0. 05 ）. There is no significant differences for recovering time between the three groups. Conclusion 8% sevoflurane used for pediatric anesthesia has the advantage of rapid induction, no peculiar smell stimulation, less influence to circulatory system, and less complications such as nausea, vomiting, excitement and low incidence, is an ideal concentration.