Multinodular goiter and parotid carcinoma : a new case of Cowden's disease |
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| Authors: | Kacem M Zili J Zakhama A Hadj Youssef F Mahjoub S Boubakri C El May M |
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| Affiliation: | Service de Médecine Interne et de Néphrologie, Monastir, Tunisie. |
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| Abstract: | Cowden's Disease is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract. We describe a 23-year-old girl who was diagnosed with this disease when she consulted for evaluation of a multinodular goiter. Further investigations revealed breast lesions, gastric polyposis and parotid cancer. Recognizing Cowden's disease is important for prompt screening for malignancies. Skin lesions are markers of precancerous development. |
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