| 蒙古族原发性高血压患者血浆中生物活性肽的测定 |
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| 引用本文： | 张雪峰,佟长青,王久亮,石淑慧.蒙古族原发性高血压患者血浆中生物活性肽的测定[J].武警医学院学报,1999(4). |
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| 作者姓名： | 张雪峰 佟长青 王久亮 石淑慧 |
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| 作者单位： | 内蒙古医学院附属医院!呼和浩特010050(张雪峰，王久亮，石淑慧)，武警医学院生理学教研室(佟长青) |
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| 摘 要： | 目的：探讨血浆中ANP、ET和CGRP在蒙古族原发性高血压发病中的作用。方法：受试者分为蒙古族高血压组、蒙古族对照组，汉族高血压组和汉族对照组，采用放射免疫法测定ANP、ET和CGRT。结果：汉族原发性高血压患者血浆ANP、ET和CGRP的浓度与对照组没有统计学意义；蒙古族原发性高血压患者血浆ANP和CGRP浓度比汉族原发性高血压患者及对照组高（P＜0．01）。结论：蒙古族原发性高血压的发病机制可能不同于汉族原发性高血压患者，血浆中ANP和CGRP浓度增加可能是蒙古族高血压患病率较高的原因之一。
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| 关 键 词： | 蒙古族 高血压 心钠素 内皮素 降钙素基因关系肽类 |
Determination of biologically active peptide in plasma of Mongolian essential hypertension patients |
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| Zhang Xuefeug, Tong Changqing, Wang Jiuliang, Shi Shuhui..Determination of biologically active peptide in plasma of Mongolian essential hypertension patients[J].Acta Academiae Medicinae CPAPF,1999(4). |
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| Authors: | Zhang Xuefeug Tong Changqing Wang Jiuliang Shi Shuhui |
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| Institution: | The First Affiliated Hospital of Inner Mongolia Medical College. Huhehaote 010050 |
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| Abstract: | objective: To explore the role of plasma ANP, ET and CGRP in the pathogenesisof Mongolian essential hypertension patients in pastoral region. Methods:Four groups of examinerswere collected according to following categories: Mongolian hypertension group , Mongolian controlgroup, Han hypertension group and Han control group. ANP, ET and CGRP were determined withradioimmunoassay. Results: The concentration of plasma ANP, ET and CGRP of Han essential hy-pertention patients were not higher than that of the control, while ANP and CGRP of the Mongo-lian essential hypertension group were higher than that of the control group and the Han essentialhypertension group. Conclusion: The mechanism of essential hypertension in Mongolian may bedifferent from that of the Han, the increased concentration of plasma ANP and CGRP may be oneof the reasons for the higher incidence of the Mongolian essential hypertension. |
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| Keywords: | Mongolian Essential hypertension Atrial natriuretic polypeptide Endothelin Calcitonin gene related peptide |
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