Usefulness of different myocardial sampling zones for the postmortem diagnosis of myocardial infarction |
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Authors: | Emilia Lachica Aurelio Luna Enrique Villanueva |
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Institution: | (1) Cátedra de Medicina Legal, University of Granada, Facultad de Medicina, Avda. de Madrid s/n, 18071 Granada, Spain;(2) Cátedra de Medicina Legal, University of Murcia, Murcia, Spain |
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Abstract: | Summary The diagnosis of myocardial infarction requires the use of a group of tests that are very efficient, quick and inexpensive. Another important consideration is the choice of myocardial sampling zones, especially in cases of differential diagnosis between a cardiac injury secondary to a trauma or violent asphyxia and others, secondary to myocardial infarction. The aim of this work was to choose, through discriminant analysis, the most useful zones of cardiac tissue for the quantification of free fatty acids and free carnitine and for the performance of the K/Na quotient, as biochemical parameters for the postmortem diagnosis of myocardial infarction. According to the discriminant analysis performed, seven zones of cardiac tissue are necessary to achieve a differential diagnosis among myocardial infarction, other natural deaths, and violent deaths with a 71.9% efficacy. Greater diagnostic efficacy was found (78.1%) for differentiating between natural deaths and violent deaths.
Offprint requests to: E. Lachica |
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Keywords: | Thanatochemistry myocardial infarction Myocardial infarction biochemical analysis |
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