儿童脑静脉窦血栓形成

以往认为,儿童脑静脉窦血栓形成(cerebral venous sinus thrombosis,CVST)是一种罕见脑血管病.随着神经影像学的发展,对儿童CVST有了更多的了解和认识.CVST的病因可分为感染性和非感染性,其临床表现多样,且缺乏特异性,这些特点使临床诊断CVST存在一定的困难.目前认为,磁共振成像联合磁共振静脉造影是诊断CVST的最佳手段.抗凝是CVST的首选治疗方法 ,对于经系统的抗凝治疗后病情仍继续恶化的患儿,可采取介入溶栓、机械取栓或去骨瓣减压术.如诊断和治疗及时,CVST的预后相对良好.

Cerebral venous sinus thrombosis in children

Cerebral venous sinus thrombosis (CVST) in children has been previously regarded as a rare cerebrovascular disease. With the development of neuroimaging, we have more knowledge and understanding about CVST in children. The etiologies of CVST can be divided into infectious and noninfectious. Its clinical manifestations are various and lack of specificity. These characteristics make the clinical diagnosis of CVST have some difficulties.Now, it is considered that in combination with magnetic resonance imaging and magnetic resonance venography is the best means of diagnosis of CVST. Anticoagulation is the preferred treatment for CVST. Interventional thrombolysis, mechanical thrombectomy or decompressive craniotomy can be used for children whose symptoms continue to deteriorate after systematic anticoagulation therapy. The prognosis of CVST is relatively good if it is diagnosed and treated in time.