抗病毒治疗代偿期肝炎肝硬化的临床观察

目的 观察抗病毒治疗代偿期肝炎肝硬化的临床疗效。方法 两组均给予保肝及免疫调节治疗，一组加服拉米夫定，每日100mg，连续12个月。另一组应用干扰素300～500万U，其中安达芬21例，运得素9例，疗程6～12个月，治疗后每3个月行上述检测及不良反应观察。结果 治疗3个月、6个月、9个月、12个月拉米夫定治疗组和干扰素组两组比较差异有显著性（P〈0．05）。拉米夫定治疗组疗效高于干扰素组。结论 拉米夫定起效快，抑制病毒作用强，短期内抗病毒疗效显著。

The efficacy of anti - retroviral therapy to decompensated cirrhosis

Objective Review of the efficacy of anti - retroviral therapy to decompensated cirrhosis. Methods Both groups were given the treatment of liver and immune regulation, a group of lamivudine plus, daily 100mg, for 12 months, the other group of Interferon, 300 - 5000000U, for 6 - 12 months. Detection and adverse reactions were observed every three months. Results There was a significant difference in two groups after 3 months, 6 months, 9 months, 12 months （P 〈0.05）. The efficacy of lamivudine in the treatment group than the interferon group. Conclusion Lamivudine had strong effect of anti - viral in the short term significantly.