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Gene therapy in the treatment of intestinal inflammation |
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| Authors: | van Montfrans Catherine te Velde Anje A van Deventer Sander J H Rodriguez Pena Maria Sol |
| Affiliation: | (1) Department of Experimental Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands |
| Abstract: | Background Local expression of anti-inflammatory or immunoregulatory genes may offer an alternative treatment of gastrointestinal inflammation.Discussion We review the basic requirements for gene therapy, the possible routes of delivery, and the different strategies for specific targeting focusing on gastrointestinal inflammation. |
| Keywords: | Gene therapy Gastrointestinal inflammation Retroviral vector Interleukin-10 |
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