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Laparoscopic Heller Myotomy Can Be Used As Primary Therapy for Esophageal Achalasia Regardless of Age
Authors:Renato Salvador  Mario Costantini  Francesco Cavallin  Lisa Zanatta  Elena Finotti  Cristina Longo  Loredana Nicoletti  Giovanni Capovilla  Romeo Bardini  Giovanni Zaninotto
Affiliation:1. Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy
3. Surgical Oncology, Istituto Oncologico Veneto, IOV-IRCCS, Padua, Italy
2. Department of General Surgery, SS Giovanni e Paolo Hospital, ULSS 12, Venice, Italy
4. Unità Operativa Complessa Chirurgia Generale, University of Padova Department of Surgery, Oncology and Gastoenterology, ULSS 12, Venice, Italy
Abstract:

Introduction

Laparoscopic Heller-Dor surgery is the current treatment of choice for patients with esophageal achalasia, but elderly patients are generally referred for less invasive treatments (pneumatic dilations or botulinum toxin injections).

Aim

To assess the effect of age on the surgical outcome of patients receiving laparoscopic Heller-Dor as primary treatment.

Methods

Demographic and clinical findings were prospectively collected on patients undergoing laparoscopic Heller-Dor from 1992 to 2012. Patients were classified in three age brackets: group A (≤45 years), group B (45–70), and group C (≥70). Treatment was defined as a failure if the postoperative symptom score was >10th percentile of the preoperative score (i.e., >8). We consecutively performed the Heller-Dor in 571 achalasia patients, 305 (53.4 %) in group A, 226 (39.6 %) in group B, and 40 (7 %) in group C.

Results

The mortality was nil; the conversion and morbidity rates were both 1.1 %. Group C patients had higher preoperative symptom scores (p?=?0.02), while the symptom duration was similar in all three groups. Mucosal tears occurred in 17 patients (3 %): 6 (2 %) in group A, 8 (3.5 %) in group B, and 3 (7.5 %) in group C (p?=?0.09). The postoperative hospital stay was slightly longer for group C (p?=?0.06).

Discussion

The treatment failure rate was quite similar: 31 failures in group A (10.1 %), 19 in group B (8.4 %), and 3 in group C (7.5 %; p?=?0.80). These failures were seen more in manometric pattern III (22.2 %, p?=?0.002). Laparoscopic Heller-Dor can be used as the first therapeutic approach to achalasia even in elderly patients with an acceptable surgical risk.
Keywords:
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