口服葡萄糖对新生儿桡动脉采血疼痛的影响

目的 探讨2种浓度葡萄糖对新生儿桡动脉采血所致疼痛的影响.方法 采用随机分组原则,将90例新生儿随机分成A、B、C3组各30例,于桡动脉采血前2 min,A组新生儿予口服10％葡萄糖2 ml,B组新生儿予口服25％葡萄糖2 ml,C组新生儿予口服白开水2ml.采用新生儿面部编码系统(NFCS)、新生儿疼痛量表(NIPS)、心率上升幅度和啼哭例数作为观测指标.结果 3组新生儿疼痛评分(包括穿刺时的NIPS评分、结束时的NFCS评分和NIPS评分)分值、心率上升幅度以及啼哭例数比较差异明显,B组明显低于A、C组,而A、C2组间比较差异无统计学意义.结论 桡动脉采血时予口服25％葡萄糖2 ml可以明显缓解新生儿疼痛,而10％葡萄糖2ml无显著镇痛作用.

Effect of oral glucose on neonatal pain during blood sampling through radial artery

Objective To explore the effect of 10％ and 25％ oral glucose on neonatal pain during blood sampling through radial artery.Methods 90 newborns were randomly divided into group A,B and C,each group with 30 cases.2 min before the blood sampling,group A was offered 2ml 10％ oral glucose,group B was offered 2ml 25％ oral glucose,and group C was offered 2ml plain boiled water by oral intake.Pain was evaluated based on Neonatal Facial Coding System (NFCS),Neonatal Infant Pain Scale(NIPS),raise of heart rate and crying cases.Results The scores of NIPS during puncture,the scores of NFCS and NIPS after puncture,the raise of heart rate and crying cases were significantly different between three groups.Group B were lower than group A and group C,while differences between group A and group C had no statistical significance.Conclusions During blood sampling through radial artery,offering newboms 2ml 25％ oral glucose can reduce the pain,while 2ml 10％ oral glucose was ineffective.