Pronóstico al año de la hemorragia subaracnoidea cortical no traumática: Serie prospectiva de 34 pacientes |
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Authors: | RF Galiano Blancart G Fortea A Pampliega Pérez S Martí V Parkhutik AV Sánchez Cruz C Soriano D Geffner Sclarsky MT Pérez Saldaña N López Hernández I Beltrán A Lago Martín |
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Institution: | 1. Servicio de Neurología, Hospital Dr. Peset, Valencia, España;2. Servicio de Neurología, Hospital La Fe, Valencia, España;3. Servicio de Neurología, Hospital General de Alicante, Alicante, España;4. Servicio de Neurología, Hospital de Sagunto, Sagunto, España;5. Servicio de Neurología, Hospital General de Castellón, Castelló de la Plana, España;6. Hospital de Manises, Manises, España |
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Abstract: | IntroductionCortical subarachnoid haemorrhage (cSAH) has multiple aetiologies. No prospective study has reported the long-term progression of the condition. The objective of this study is to describe the clinical and aetiological characteristics of patients with cSAH and to gain insight into prognosis.MethodsWe performed a prospective, observational, multi-centre study. Data on clinical and radiological variables were collected; during a one-year follow-up period, we recorded data on mortality, dependence, rebleeding, and the appearance of dementia.ResultsThe study included 34 patients (mean age, 68.3 years; range, 27-89). The most frequent symptoms were headache and focal neurological deficits, which were frequently transient and recurrent. CT scans returned pathological findings in 28 patients (85%). Brain MRI scans were performed in 30 patients (88%), revealing acute ischaemia in 10 (29%), old haemorrhage in 7 (21%), and superficial siderosis in 2 (6%). Aetiology was identified in 26 patients (76.5%): causes were cerebral amyloid angiopathy in 8, ischaemic stroke in 5, vasculitis in 4, reversible posterior encephalopathy in 2, venous thrombosis in 2, reversible cerebral vasoconstriction syndrome in 2, carotid occlusion in 1, Marfan syndrome in 1, and meningeal carcinomatosis in 1. Three patients died during follow-up (2 due to causes related to the cause of cSAH). Three patients developed dementia, 3 had lobar haemorrhages, and one had a second cSAH.ConclusionsThe most frequent causes of cSAH in our series were cerebral amyloid angiopathy, ischaemic stroke, and vasculitis. This type of haemorrhage has a worse prognosis than other non-aneurysmal cSAH. There are numerous possible causes, and prognosis depends on the aetiology. In elderly patients, intracranial haemorrhage is frequently associated with cognitive impairment. |
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Keywords: | Cortical subarachnoid haemorrhage Non-traumatic subarachnoid haemorrhage Cerebral amyloid angiopathy Prognosis Ischaemic stroke Aetiology |
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