Hyperbaric oxygen therapy for the placement of dental implants in irradiated patients: systematic review and meta-analysis |
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| Authors: | A.F. Benites Condezo R.Z. Araujo D.H. Koga M.M. Curi C.L. Cardoso |
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| Affiliation: | 1. Department of Oral Surgery, UNISAGRADO, Bauru, São Paulo, Brazil;2. Department of Oral Implantology and Prosthesis, Universidade Federal of Uberlândia, Uberlândia, Brazil;3. Department of Stomatology, Hospital Santa Catarina, São Paulo, Brazil;1. Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy;2. Operative Unit of Maxillofacial Surgery, Bellaria-Maggiore Hospitals, Bologna, Italy;3. Department of Public Health, Federico II University of Naples, Naples, Italy;4. Operative Unit of Maxillofacial Surgery, University of Sassari, Viale San Pietro 43/b, Sassari, Italy;5. Department of Neurosurgery, University of Salerno, Salerno, Italy;1. Regional Maxillofacial Unit, Aintree University Hospital, Liverpool, UK;2. Department of Molecular and Clinical Cancer Medicine, Northwest Cancer Research Centre, University of Liverpool, Liverpool, UK;1. Department of Oral And Maxillofacial Surgery, Dental School, Qazvin University of Medical Sciences, Qazvin, Iran;2. Private Practice;3. Department of Pediatric Dentistry, Dental School, Qazvin University Of Medical Sciences, Qazvin, Iran;1. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gaziosmanpasa University, Tokat, Turkey;2. Department of Veterinary Genetics, Faculty of Veterinary, Ondokuz May?s University, Samsun, Turkey;3. Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey;4. Department of Medical Genetics, Faculty of Medicine, Hitit University, Corum, Turkey;5. Department of Medical Biology, Faculty of Medicine, Aksaray University, Aksaray, Turkey |
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| Abstract: | This study was a systematic review with meta-analysis to evaluate the influence of hyperbaric oxygen therapy (HBOT) on the survival of dental implants placed in patients who had had radiotherapy for cancer of the head and neck. A systematic literature search was conducted using the PubMed/Medline, Science Direct, Embase and the Cochrane Library, between January 1985 and July 2018. The study observed the PRISMA (Preferred Reporting Items for Systematic review and Meta-Analysis) declaration and norms, and the systematic review was duly recorded in the PROSPERO (International prospective register of systematic reviews) database. Inclusion and exclusion criteria were applied, and all articles were selected on the basis of PICO questions. The process of eligibility and quality evaluation yielded three studies for statistical analysis. Based on the survival rates, there was no evidence that the risk of an implant failing was different between the patients who received HBOT and those who did not. Moreover, the risk of an implant failing did not depend on the anatomical site. HBOT exerted no beneficial influence on the survival rates of implants placed in irradiated patients, and the risk of an implant failing did not depend on its location. |
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| Keywords: | Dental implants Irradiation Systematic review Hyperbaric oxygenation |
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