Epidemiologic Survey of Kawasaki Disease in Jilin from 1999 Through 2008 |
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Authors: | Xiaomei Zhang Zhen Zhang Shicheng Liu Jinghui Sun |
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Institution: | (1) Department of Pediatrics, The First Hospital of Jilin University, 71 Xin Min Street, Changchun, 130021, Jilin, China; |
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Abstract: | The epidemiologic pictures of Kawasaki disease (KD) in Jilin Province of China is still not clear. We sent a questionnaire
form and diagnostic guidelines for KD to the province's 32 hospitals above the county and city level with pediatric in-patients.
All patients with KD diagnosed during January 1999 through December 2008 were recruited in this survey. The incidence of KD
was 1.39 to 11.07 (5.26 ± 3.97) per 100,000 children under the age of 5 years between 1999 and 2008. The ratio of male to
female was 1.96 to 1. Ages at onset ranged from 58 days to 14 years. Patients under 5 years of age accounted of 88.73%. The
disease occurred throughout the year, but it occurred more frequently in May to July and November. The most common cardiac
abnormality was coronary artery dilatation (49.5%). Age at onset and hypoalbuminemia (<30 g/l) were selected for multivariate
logistic regression equation. In conclusion, incidences of KD increased in Jilin Province. Age and gender distribution shared
similarities with previous reports, and the seasonal distribution was different. Age and lower serum albumin were the most
important risk factors of coronary arterial lesions (CAL) in KD. In addition, patients treated with steroids also had a possible
heightened risk of contracting CAL. |
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