| 趋化因子及其受体在炎症性肠病中的作用 |
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| 引用本文： | 钟万锷,周国雄. 趋化因子及其受体在炎症性肠病中的作用[J]. 国际消化病杂志, 2007, 27(6): 443-445 |
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| 作者姓名： | 钟万锷 周国雄 |
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| 作者单位： | 南通大学附属医院消化内科,226001;南通大学附属医院消化内科,226001 |
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| 摘 要： | 趋化因子是一类控制细胞定向迁移的细胞因子,其功能行使由趋化因子受体介导。在炎症性肠病中,许多趋化因子及其受体表达增加,并在发病机制上起着重要作用。针对趋化因子及其受体的靶向治疗能减轻炎症损伤,可望成为一种新的炎症性肠病的治疗方法。
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| 关 键 词： | 趋化因子 趋化因子受体 炎症性肠病 |
| 修稿时间： | 2007-01-12 |
The role of chemokines and their receptors in inflammatory bowel disease |
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| ZHONG Wan-e,ZHOU Guo-xiong. The role of chemokines and their receptors in inflammatory bowel disease[J]. International Journal of Digestive Disease, 2007, 27(6): 443-445 |
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| Authors: | ZHONG Wan-e ZHOU Guo-xiong |
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| Abstract: | Chemokines are chemotactic cytokines that can direct cells trafficking, conducting their functions via chemokine receptors. Many chemokines and their receptors show increased expression in inflammatory bowel disease, which play an important role in the pathogenesis of the disease. Targeted therapy that aims directly at chemokines and their receptors can ameliorate inflammatory damage, and can be a novel therapeutics for inflammatory bowel disease. |
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| Keywords: | Chemokine Chemokine receptor Inflammatory bowel disease |
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