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Schizophrenia with prominent catatonic features ('catatonic schizophrenia'). II. Factor analysis of the catatonic syndrome
Authors:Ungvari Gabor S  Goggins William  Leung Siu-Kau  Gerevich Jozsef
Institution:Department of Psychiatry, Chinese University of Hong Kong, China. gsungvari@cuhk.edu.hk
Abstract:Previous factor analyses of catatonia have yielded conflicting results for several reasons including small and/or diagnostically heterogeneous samples and incomparability or lack of standardized assessment. This study examined the factor structure of catatonia in a large, diagnostically homogenous sample of patients with chronic schizophrenia using standardized rating instruments. A random sample of 225 Chinese inpatients diagnosed with schizophrenia according to DSM-IV criteria were selected from the long-stay wards of a psychiatric hospital. They were assessed with a battery of rating scales measuring psychopathology, extrapyramidal motor status, and level of functioning. Catatonia was rated using the Bush-Francis Catatonia Rating Scale. Factor analysis using principal component analysis and Varimax rotation with Kaiser normalization was performed. Four factors were identified with Eigenvalues of 3.27, 2.58, 2.28 and 1.88. The percentage of variance explained by each of the four factors was 15.9%, 12.0%, 11.8% and 10.2% respectively, and together they explained 49.9% of the total variance. Factor 1 loaded on "negative/withdrawn" phenomena, Factor 2 on "automatic" phenomena, Factor 3 on "repetitive/echo" phenomena and Factor 4 on "agitated/resistive" phenomena. In multivariate linear regression analysis negative symptoms and akinesia were associated with 'negative' catatonic symptoms, antipsychotic doses and atypical antipsychotics with 'automatic' symptoms, length of current admission, severity of psychopathology and younger age at onset with 'repetitive' symptoms and age, poor functioning and severity of psychopathology with 'agitated' catatonic symptom scores. The results support recent findings that four main factors underlie catatonic signs/symptoms in chronic schizophrenia.
Keywords:AIMS  Abnormal Involuntary Movement Scale  BARS  Barnes Akathisia Rating Scale  BFCRS  Bush–Francis Catatonia Rating Scale  BPRS  Brief Psychiatric Rating Scale  CGI  Clinical Global Impression  EPS  Extrapyramidal Side Effects  GAS  Global Assessment Scale  HDRS  Hamilton Depression Rating Scale  NOSIE  Nurses' Observation Scale for Inpatient Evaluation  SANS  Scale for the Assessment of Negative Symptoms  SAS  Simpson–Angus Extrapyramidal Side Effects Scale  VPARS  Van Putten Akinesia Rating Scale  YBOCS  Yale–Brown Obsessive-Compulsive Rating Scale  
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