Normalization of auditory evoked potential and visual evoked potential in patients with idiot savant |
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Authors: | Chen X Zhang M Wang J Lou F Liang J |
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Institution: | Shanghai Institute of Mental Health, Shanghai 200030, China. |
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Abstract: | Objective To investigate the variations of auditory evoked
potentials (AEP) and visual evoked potentials (VEP) of patients with idiot savant (IS) syndrome.
Methods Both AEP and VEP were recorded from 7 patients with IS syndrome, 21 mentally
retarded (MR) children without the syndrome and 21 normally age matched controls, using a
Dantec concerto SEEG 16 BEAM instrument. Results Both AEP and VEP of MR group showed
significantly longer latencies (P1 and P2 latencies of AEP, P<0.01; N1 and N2 latencies of VEP,
P< 0.01/0.05), lower P2 amplitudes (P<0.01) and higher P3 amplitudes (P<0.01), as compared
with normal controls. But none of above mentioned changes was found with IS group. Almost
all MR patients (90.1%) presented P4 component in both AEP and VEP, which was also in sharp
contrast with its incidence in other 2 groups (IS: 14.3%; normal controls: 9.5%). Conclusion
Patients with idiot savant syndrome presented normalized AEP and VEP. |
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Keywords: | |
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