| 一个新型α1-去甲肾上腺素受体的光亲和放射性碘探针的母体化合物的合成 |
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| 引用本文： | 黄培强,BRouot,RWylde,BCastro.一个新型α1-去甲肾上腺素受体的光亲和放射性碘探针的母体化合物的合成[J].药学学报,1992,27(11):864-866. |
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| 作者姓名： | 黄培强 BRouot RWylde BCastro |
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| 作者单位： | 厦门大学化学系,厦门361005;*CentreCNRS-INSERMdePharmacologie-Endocrinologie,RuedelaCatdonille,34094Montpelliercedex-05,France |
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| 摘 要： | A new and high-yielding procedure was described for the synthesis of 4-amino-6,7-dimethoxy-24-4 (4-aminophenyl) butanoyl]-1-piperazinyl]-quinazoline Ⅶ, the key intermedi-ate for the newly designed potential α1-AR affinity/photoaffinity probes Ⅷa/Ⅸa.
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| 关 键 词： | α1-去甲肾上腺素受体 光亲和标记 哌唑嗪 |
| 收稿时间： | 1992-01-03 |
Synthesis of the key intermediate for a new radioiodinated photoaffinity probe for alpha 1-adrenergic receptor] |
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| PQ Huang,B Rouot,R Wylde,B Castro.Synthesis of the key intermediate for a new radioiodinated photoaffinity probe for alpha 1-adrenergic receptor][J].Acta Pharmaceutica Sinica,1992,27(11):864-866. |
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| Authors: | PQ Huang B Rouot R Wylde B Castro |
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| Institution: | Department of Chemistry, Xiamen University. |
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| Abstract: | A new and high-yielding procedure was described for the synthesis of 4-amino-6,7-dimethoxy-24-4 (4-aminophenyl) butanoyl]-1-piperazinyl]-quinazoline Ⅶ, the key intermedi-ate for the newly designed potential α1-AR affinity/photoaffinity probes Ⅷa/Ⅸa. |
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| Keywords: | Photoaffinity label Prazosin α1--Adrenergic receptor |
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