| 依那普利和吲哒帕胺联用对高血压伴左室肥厚的疗效观察 |
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| 引用本文： | 佘子岳,ZHAO Huibin,佘子瑜.依那普利和吲哒帕胺联用对高血压伴左室肥厚的疗效观察[J].中国现代医生,2008,46(14):23-24. |
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| 作者姓名： | 佘子岳 ZHAO Huibin 佘子瑜 |
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| 作者单位： | 1. 中山大学附属第五医院药剂科,广东珠海,519000
2. 广东省中山市人民医院心血管内科,广东中山,528403 |
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| 摘 要： | 目的观察依那普利和吲哒帕胺对高血压合并左心室肥厚患者的降压及逆转LVH的效果。方法选择58例高血压并LVH患者，给予依那普利和吲哒帕胺联合治疗32周。观察治疗前后的血压、动态血压及患者的IVST、LVPWT、LVDd、LVMI。结果治疗后患者收缩压、舒张压、24h收缩压、24h舒张压明显下降。治疗后患者IVST、LVPWT、LVDd、LVMI值较治疗前减少（P〈0．05）。结论依那普利和吲哒帕胺合用有较好的降压及逆转LVH的作用。
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| 关 键 词： | 依那普利 吲哒帕胺 高血压 左心室肥厚 降压 |
Observation of Enalapril and Indapamide in Hypertension Associated with Left Ventricular Hypertrophy |
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| Authors: | YU Ziyue ZHAO Huibin YU Ziyu |
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| Institution: | YU Ziyue, ZHAO Huibin, YU Ziyu (1. Department of Pharmacy, the Fifth Affiliated Hospital of Zhongshan university, Guangdong 519000; 2. Medical Department of Cardiovascular, the People＇s Hospital of Zhongshan,Guangdong 528403) |
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| Abstract: | Objective to observe the effect of enalapril and indapamide in hypertension associated with left ventricular hypertrophy. Methods 58 cases with hypertension associated with left ventricular hypertrophy were chosen which were given enalapril combined with indapamide for 32 weeks; blood pressure, dynamic blood pressure,LVDd,IVST,LVPWT, LVMI were observed. Results systolic pressure, diastolic pressure, decreased after treatment, the value of LVDd,IVST,LVPWT,LVMI reduced. Conclusion nalapril and indapamide in hypertension associated with left ventricular hypertrophy have the effect of good antihypertensive and reverse LVH. |
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| Keywords: | Enalapril Indapamide Hypertension Left ventricular hypertrophy |
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