| 前脂肪细胞因子-1对糖脂代谢的影响 |
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| 引用本文： | 夏常青,方朝晖. 前脂肪细胞因子-1对糖脂代谢的影响[J]. 中国全科医学, 2007, 10(20): 1741-1743 |
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| 作者姓名： | 夏常青 方朝晖 |
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| 作者单位： | 安徽中医学院第一附属医院,安徽省合肥市,230038 |
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| 摘 要： | 前脂肪细胞因子-1(preadipocyte factor1,Pref-1)是脂肪细胞分化早期具有分化抑制作用的分子标志,而脂肪细胞的分化障碍不仅能够导致脂代谢障碍,还可以使糖尿病的易患性增加,导致肥胖、脂肪营养不良、糖尿病等代谢性疾病。本文就Pref-1的结构、表达、其在脂肪细胞分化中的作用及其对糖、脂代谢的影响进行综述。
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| 关 键 词： | 前脂肪细胞因子-1 细胞分化 葡萄糖代谢障碍 脂肪细胞 |
| 文章编号： | 1007-9572（2007）20-1741-03 |
| 修稿时间： | 2007-07-15 |
The Effect of Pre - Adipocyte Factor - 1 on Glucolipid Metabolic Disorders |
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| XIA Chang-qing,FANG Zhao-hui. The Effect of Pre - Adipocyte Factor - 1 on Glucolipid Metabolic Disorders[J]. Chinese General Practice, 2007, 10(20): 1741-1743 |
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| Authors: | XIA Chang-qing FANG Zhao-hui |
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| Affiliation: | The First Affiliated Hospital of Traditional Chinese Medical College of Anhui, Hefei 230038, China |
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| Abstract: | Pre-adipocyte factor 1(Pref-1)serves as a molecular marker,which can inhibit adipogenesis during the nonage of adipocyte differentiation.However,adipocyte dysdifferentiation not only leads to lipoidosis,but also increases the affectability of diabetes,and leads to metabolic disorders,such as obesity,lipodystrophy and diabetes,etc.This study is a review of the structure and expression of Pref-1,and its effects on adipocyte differentiation and glucolipid metabolism. |
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| Keywords: | Pre-adipocyte factor-1 Cell differentiation Glucose metabolism disorders Adipocytes |
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