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大肠癌个体化化疗方案的实验研究
引用本文:史本彩,纪忠岐. 大肠癌个体化化疗方案的实验研究[J]. 河南大学学报(医学版), 2003, 22(3): 12-12
作者姓名:史本彩  纪忠岐
作者单位:1. 河南大学医学院,形态实验室,河南,开封,475001
2. 河南大学药学院,药理教研室,河南,开封,475001
摘    要:日的:探讨大肠癌个体化疗方案。方法:大肠癌原代培养,MTT法进行药敏试验。结果:发现5一Fu和MMC有效率最高,MMC次之。结论:大肠癌的化疗中,在缺乏药敏实验的情况下,建议采用5一Fu+MMC的联合化疗方案。

关 键 词:MTT法  大肠肿瘤  化学疗法  药敏试验
文章编号:1008-2867(2003)03-0012-01
修稿时间:2003-04-25

Experimental study on the Pattern of individual chemotherapy for large intestine carcinoma
SHI Ben - cai,JI Zhong - qi. Experimental study on the Pattern of individual chemotherapy for large intestine carcinoma[J]. Journal of Henan University, 2003, 22(3): 12-12
Authors:SHI Ben - cai  JI Zhong - qi
Abstract:Objective: To explore the pattern of individual chemotherapy for large intestine carcinoma. Methods: The tissues of large intestine carcinoma were used as original cultures, and the experiments on sensitivity to medicines were done with MTT. Results: The findings suggested that 5 - FU and MMC had the less effects than those of other methods. Conclusion: In the chemotherapy of large intestine carcimoma, it is suggested that the combination chemotherapy pattern 5 - FU + MMC be used in short of medicine sensitivity experiment.
Keywords:MTT methods  large intestine carcinoma  chemotherapy  sensitivity to medicines
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