Effects of PEEP on cardiovascular dynamics after open-heart surgery: a new postoperative monitoring technique. |
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Authors: | T A Angerpointner A E Farnsworth B T Williams |
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Affiliation: | From the Department of Cardiothoracic Surgery, St Thomas Hospital, Lambeth Palace Rd, London, England |
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Abstract: | The circulatory effects of incremental increases in positive end-expiratory pressure ventilation (PEEP) were assessed on 11 occasions in post-operative cardiac surgical patients by phasic aortic blood flow measurements and high-fidelity pressure recordings from which flow and pressure-flow derivatives of cardiac performance were calculated. At 15 cm H2O PEEP, mean arterial blood pressure was decreased by 10%, stroke volume and cardiac output by 15%, and peak left ventricular power by 21%. Although these indices promptly returned to control levels when PEEP was discontinued, levels of PEEP above 10 cm H2O should be used with caution for this group of patients. |
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Keywords: | Address reprint requests to Mr. Williams Department of Cardiothoracic Surgery St Thomas' Hospital London SE1 7EH England |
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